Construction of 1-pyrroline skeletons by Lewis acid-mediated conjugate addition of vinyl azides.
نویسندگان
چکیده
Lewis acid-mediated conjugate addition of vinyl azides to electron-deficient alkenes led to the efficient construction of 1-pyrroline skeletons. The reactions of vinyl azides with 3-alkylidene-2-oxoindolines afford 3',4'-dihydrospiro[indoline-3,2'-pyrrol]-2-ones in a diastereoselective fashion, whereas those with dimethyl 2-alkylidenemalonates provide 4,5-dihydro-3H-pyrroles.
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ورودعنوان ژورنال:
- Chemical communications
دوره 52 12 شماره
صفحات -
تاریخ انتشار 2016